House Speaker Nancy Pelosi is obviously sick and tired of claims that Rep. Alexandria Ocasio-Cortez is the leader of the Democratic Party.

While speaking to an audience on Monday at the London School of Economics and Political Science, the California Democrat said she has talked to ultra-progressive lawmakers like Ocasio-Cortez about the importance of appealing to voters in centrist districts who do not support socialist measures such as the Green new Deal and Medicare for All.

“This is about winning. When we have to go into the districts we have to win, we have to cull that to what we have in common with those people,” Pelosi said.

Pelosi then explained that Ocasio-Cortez’s district in New York is so liberal that a glass of water with “Democrat” next to it could win an election there.

“This glass of water would win with a ‘D’ next to it in those districts. But that’s not where we have to win elections,” Pelosi added, arguing in favor of supporting moderate Democrats who can win in Republican-held districts.

This is the third time in less than a week that Pelosi has savaged Ocasio-Cortez.

During an interview Sunday on CBS’ 60 Minutes, Pelosi was asked by host Lesley Stahl about Ocasio-Cortez’s growing power in the Democratic Party.

Stahl asked Pelosi about whether she has done an effective job unifying the different factions, such as moderates, progressives, and socialists — all of which have different agendas.

“So you are contending with a group in Congress: Over here on the left flank are these self-described socialists, on the right, these moderates,” Stahl said. “And you yourself said that you’re the only one who can unify everybody. And the question is can you?”

Pelosi replied, “By and large, whatever orientation they came to Congress with, they know that we have to hold the center. That we have to be m– go down the mainstream.”

Stahl then pointed out that it sure looks like the Democratic Party is “fractured.”

“You have these wings – AOC, and her group on one side,” Stahl began.

“That’s like five people,” Pelosi fired back, donning a smirk on her face.

Pelosi also waved off the claim that her party is adopting socialism, saying it is “not the view of the Democratic Party.”

During an interview last week with USA Today, the House Speaker noted that congressional votes are far more powerful than Twitter followers — a dig at Ocasio-Cortez’s massive social media following.

“While there are people who have a large number of Twitter followers, what’s important is that we have a large number of votes on the floor of the House,” Pelosi said.